主管:国家卫生健康委员会
主办:国家卫生健康委医院管理研究所
中国科技核心期刊(中国科技论文统计源期刊)
中国科学引文数据库(CSCD)核心库期刊
《中文核心期刊要目总览》核心期刊

中国护理管理 ›› 2025, Vol. 25 ›› Issue (12): 1903-1908.doi: 10.3969/j.issn.1672-1756.2025.12.028

• 综述 • 上一篇    下一篇

数字生物标志物在老年人认知衰弱早期识别中的应用进展

刘雨骅 徐琰 韩斌如   

  1. 首都医科大学宣武医院护理部,国家老年疾病临床医学研究中心,100053 北京市
  • 出版日期:2025-12-15 发布日期:2025-12-15
  • 通讯作者: 韩斌如,硕士,主任护师,博士生导师,护理部主任,E-mail:hanbinru8723@163.com
  • 作者简介:刘雨骅,硕士在读
  • 基金资助:
    北京市科技计划项目(Z241100007724008);北京市卫生健康科技成果和适宜技术推广项目(BHTPP2024095)

Application progress of digital biomarkers in early recognition of cognitive frailty for older adults

LIU Yuhua, XU Yan, HAN Binru   

  1. Department of Nursing, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing, 100053, China
  • Online:2025-12-15 Published:2025-12-15
  • Contact: E-mail:hanbinru8723@163.com

摘要: 认知衰弱是阿尔茨海默病的重要预测因素,具有可逆性或潜在可逆性,早期识别和干预对延缓疾病的发生发展至关重要。随着数字健康技术的快速进步,数字生物标志物技术越来越多地应用于疾病的早期检测中,通过可穿戴设备和移动应用提供客观、连续且高精度的数据,能够实时监测健康状态的变化,成为认知衰弱早期检测的重要工具。文章综述了数字生物标志物在老年人认知衰弱评估中的应用进展,旨在为早期识别、风险预测及个性化治疗方案的优化提供科学依据。

关键词: 老年人;认知衰弱;数字生物标志物;早期识别;综述

Abstract: Cognitive frailty is an important predictor of Alzheimer's Disease, which is reversible or potentially reversible, and early identification and intervention are crucial to slow down the development of the disease. With the rapid advancement of digital health technologies, digital biomarkers are increasingly used in the early detection of diseases to provide objective, continuous and high-precision data through wearable devices and mobile applications, capable of real-time monitoring of changes in health status. As a consequence, they have become an important tool for the early detection of cognitive frailty. This article reviews the latest progress of digital biomarkers in the assessment of cognitive frailty in the elderly, aiming to provide a scientific basis for early identification, risk prediction and optimization of personalized treatment plans.

Key words: older adult; cognitive frailty; digital biomarker; early identification; review

中图分类号:  R47;R197