Abstract: Objective: To explore the impact of the hyper-Enhanced Recovery After Surgery (hyper-ERAS) care model on postoperative recovery in colorectal cancer surgery patients in order to provide a reference for optimizing perioperative management and accelerate patient recovery. Methods: Convenience sampling was used to enroll 69 eligible colorectal cancer surgery patients from January to March 2023 as the ERAS group, who received ERAS perioperative care; from April to August 2023, 72 patients were enrolled as the hyper-ERAS group, who received hyper-ERAS perioperative care. The postoperative rehabilitation status and the incidence rates of postoperative complications of the two groups were compared. Results: The hyper-ERAS group had a significantly shorter time to first flatus [17.21 (11.80, 36.00) h], first defecation [37.61 (25.48, 56.33) h], and postoperative hospital stay [(2.11±0.98) days], and lower treatment cost [7.60 (6.71, 8.25) ten thousand yuan] compared with the ERAS group [53.89 (32.21, 60.21) h, 75.30 (55.67, 100.88) h, (6.24 ± 2.20) days, and 9.06 (8.26, 9.71) ten thousand yuan, respectively] (all P<0.001). There was no statistically significant difference in incidence rates of postoperative complications between the two groups (all P>0.05). Conclusion: The application of the hyper-ERAS care model in the perioperative period of colorectal cancer patients has a good clinical effect. This model can promote early recovery, shorten hospital stay, and save hospitalization costs.

Key words: colorectal cancer, Enhanced Recovery After Surgery, hyper Enhanced Recovery After Surgery, perioperative nursing