Abstract: Objective: To design and develop a mobile health management platform for weight management in breast cancer patients and to test its usability, aiming to provide support for remote exercise rehabilitation of breast cancer patients. Methods: Based on a 12-week weight management exercise intervention program for breast cancer patients, "Breast Health Guardian" mobile health management platform was developed to realize remote management of exercise rehabilitation of breast cancer. Using purposive sampling method, 13 patients were enrolled for a three-month trial of the App to assess usability through questionnaires and open-ended questions. Results: The "Breast Health Guardian" mobile health management platform was developed, consisting of a mobile application and a computer-based data management system. The App includes a patient interface and a nurse interface. The main function is to provide personalized exercise prescription and dynamic exercise monitoring for breast cancer patients. The usability evaluation was positive, with the mean score and 95% CI of the usability evaluation questionnaire score was 2.12 (1.49-2.76). Conclusion: The mobile health management platform for weight management in breast cancer patients can achieve efficient implementation of weight management and exercise interventions. It offers a good user experience and has good usability.

Key words: breast cancer; obesity; weight management; mobile health; exercise prescription