Abstract: Objective: To analyze the current status and existing problems of clinical practice among blood purification nurses in Xizang Autonomous Region, so as to provide references for the rational allocation of blood purification nursing human resources in Xizang Autonomous Region. Methods: From July to October 2025, a total of 85 blood purification nurses from 13 hospitals in the Xizang Autonomous Region were recruited by convenience sampling and investigated with a self-designed questionnaire. Results: In total, 63.53% of blood purification nurses were concentrated in Lhasa, and 90.59% in public hospitals. The nursing team was mainly composed of young and middle-aged nurses aged 31-<40 years (54.12%) and those with bachelor’s degree or above (76.47%), while nurses with senior professional title only accounted for 3.53%. The average time proportion allocated to clinical nursing, nursing education, nursing research and nursing management was 71.77%, 8.65%, 2.58% and 17.00%, respectively. The number of years in practice was the key factor influencing nurses' participation rate in advanced practice. Conclusion: The structure of blood purification nurses in the Xizang Autonomous Region is imbalanced, and their participation in advanced practice is insufficient. It is necessary to establish an evidence-based, nurse-centered, and regionally collaborative plateau-adaptive management model in the future.

Key words: plateau nursing; hemodialysis; human resource management; resource allocation