Abstract: Objective: To explore the latent profiles of pain self-efficacy in patients with gout and to analyze its relationship with personal mastery, so as to provide a reference for the development of a pain self-efficacy intervention program for patients. Methods: From September to December 2023, 234 gout patients in Shandong province were conveniently selected as the research subjects. A survey was administered using the General Information Questionnaire, the Pain Self-Efficacy Scale, and the Personal Mastery Scale. Then we analyzed and categorized pain self-efficacy, and determined the relationship between latent profiles of pain self-efficacy and personal mastery. Results: The pain self-efficacy of patients with gout could be categorized into three categories: low self-efficacy-low daily functioning type (29.91%), medium self-efficacy-balanced type (43.16%), and high self-efficacy type (26.92%). There were statistically significant differences between patients with different pain self-efficacy latent profiles in terms of age, education level, per capita monthly household income, place of residence, number of gout attacks in the past year, tophi, comorbidities and personal mastery (all P<0.05), and the personal mastery was an independent influencing factor of the latent profiles (P<0.05). Conclusion: Pain self-efficacy of patients with gout is heterogeneous. Therefore, targeted interventions should be taken to improve their personal mastery to improve their pain self-efficacy.

Key words: gout; pain self-efficacy; personal mastery; latent profile analysis