Abstract: Pressure injury (Pressure sores/Pressure ulcer) is a potentially preventable but common adverse event which can cause pain, discomfort, anxiety to patients and add significant costs to the healthcare system. In November 2019, the third edition of the Prevention and Treatment of Pressure Ulcers/Injuries: Clinical Practice Guideline developed jointly by the European Pressure Ulcer Advisory Panel, the National Pressure Injury Advisory Panel, and the Pan Pacific Pressure Injury Alliance was officially published. Built on the research evidences included in the 2014 edition, the 2019 edition of the guideline was developed using a revised methodology which expanded the inclusion scope of study, and made recommendations that reflected the latest evidences. This article will summarize the key contents of the 2019 edition of the guideline, and compare the updated content against the previous edition which will hopefully help clinicians and caregivers develop a clear understanding of the updated content of the latest guideline. It is also hoped that this understanding and awareness will promote better uptake of the international clinical practice guideline which may ultimately improve clinical practice in the prevention and treatment of pressure injuries.

Key words: pressure injury; prevention; treatment; guideline; interpretation