Abstract: Objective: To investigate the status of Mild Cognitive Impairment (MCI) in non-dialysis outpatients with Chronic Kidney Disease (CKD) and explore its influencing factors. Methods: Totally 214 outpatients with non-dialysis CKD were investigated from December 2018 to January 2020 using Montreal Cognitive Assessment (MoCA) Questionnaire. Convenient sampling method was performed. The MCI status was evaluated and the influencing factors were explored. Results: The average MCI score of the CKD patients was 24.24±3.95. Totally 117 (54.7%) CKD patients were diagnosed as MCI. Binary logistic regression analysis showed that old age, CKD stage, education level, occupation status, regular exercise and payment of medical expenses were influencing factors of MCI in CKD patients. Conclusion: More than half of pre-dialysis CKD patients have developed MCI. Therefore, nursing staff should pay attention to the screening of MCI in CKD patients, and carry out targeted intervention, in order to reduce the adverse prognosis caused by MCI.

Key words: non-dialysis; Chronic Kidney Disease; Mild Cognitive Impairment; status investigation; influencing factors