Abstract: Objective: To investigate the current status of defeat and its influencing factors in female infertility patients with In Vitro Fertilization-Embryo Transfer (IVF-ET). Methods: A total of 284 female infertility patients with IVF-ET at a reproductive medicine center in Changsha from July 2019 to November 2019 were enrolled in the survey using the General Information Questionnaire, the Chinese version of the Defeat Scale, Patient Health Questionnaire (PHQ-9), and Locke-Wollance Marriage Adjustment Test (MAT). Results: The score of defeat of 284 female infertility patients was 26.10±6.31. The multiple linear stepwise regression analysis showed that the main influencing factors of the defeat in female infertility patients with IVF-ET were the years of infertility, depression, total number of IVF-ET treatments and the marital adjustment of the couple (P<0.05), explaining 83.2% of the total variation. Conclusion: The level of defeat is high in female infertility patients with IVF-ET. Medical professionals should focus on targeted psychological interventions for the high psychological defeat of female infertility patients who are in the treatment phase to improve their treatment confidence and status.

Key words: defeat; infertility; marital adjustment; depression; assisted reproduction