Abstract: In order to meet the increasing rehabilitation needs of cancer patients, a cognition assessment and rehabilitation system based on Virtual Reality (VR) technology for cancer patients was developed. This VR system overcomes the limitations of traditional cognitive assessment and rehabilitation training, which are lack of fun, unmet individual needs, and low ecological validity. This VR cognition assessment and rehabilitation system includes three modules: cognitive assessment, cognitive rehabilitation intervention and cognitive function evaluation. A preliminary application was performed in 21 participants to test the stability and safety of this system. The results showed that the participants can complete the cognitive rehabilitation tasks in the virtual environment freely and comfortably. Compared with the traditional format assessment such as paper and pencil-based format, the participants prefer to use VR for cognitive assessment. And there were no adverse events happened related to VR equipment. Therefore, applying VR technology to cognition assessment and rehabilitation for cancer patients is feasible, acceptable and safe, but future research is needed to examine the effectiveness of this VR cognitive assessment and rehabilitation system for cancer patients.

Key words: Virtual Reality; cancer-related cognitive impairment; cancer rehabilitation