关键词: 妊娠期糖尿病；复发；危险因素；再妊娠

Abstract: Objective: To explore risk factors which can predict the recurrence of Gestational Diabetes Mellitus (GDM). Methods: We evaluated women who experienced GDM in the previous pregnancy and had the subsequent pregnancy in our hospital between January 2010 and March 2020. A total of 269 women were finally included, 132 women with recurrent GDM were enrolled into the experiment group, while 137 women without recurrent GDM as the control group. Logistic regression analysis was performed to identify the independent risk factors of recurrent GDM and the Receiver Operating Characteristic (ROC) curve was applied to evaluate the predictive values. Results: The frequency of recurrent GDM in subsequent pregnancies was 49.1%. Logistic regression revealed that both neonatal birthweight in the index pregnancy and weight change between pregnancies were independent predictors of recurrent GDM (P<0.001). Moreover, the Area Under the Curve (AUC) of neonatal birthweight in the index pregnancy and weight change between pregnancies for predicting recurrent GDM were 0.684 and 0.702 respectively, the AUC of these two combined factors was 0.760. Conclusion: GDM is a common complication with high recurrence, targeted nursing interventions should be carried out to reduce recurrence risks and improve the pregnancy outcomes.

Key words: Gestational Diabetes Mellitus; recurrence; risk factors; subsequent pregnancy