Abstract: Objective: To construct a cognitive function intervention program for ICU patients with Subsyndromal Delirium and to verify its clinical application effect. Methods: Based on evidence-based construction of cognitive function intervention program for Subsyndromal Delirium patients. 222 cases of sublingual patients in ICU of a tertiary grade A hospital were conveniently selected as study subjects. The control group (113 cases) received routine nursing measures, and the intervention group (109 cases) received the cognitive function intervention program for patients with Subsyndromal Delirium. The differences in duration of subsyndromal, conversion rate, incidence of delirium, cognitive function, sleep quality, length of hospital stay and mechanical ventilation between the two groups were compared. Results: After intervention, the duration of Subsyndromal Delirium was decreased, the conversion rate was increased, the incidence of delirium was decreased, and the cognitive function was improved (P<0.05). There was no significant difference in sleep quality, length of hospital stay and mechanical ventilation between the two groups (P>0.05). Conclusion: The cognitive intervention program is clinically operability. The implementation of the program is beneficial to improve the outcome and enhance the cognitive level of patients, but the effect of the program on the sleep quality, the length of mechanical ventilation and the length of hospital stay is not significant.

Key words: Intensive Care Unit; Subsyndromal Delirium; cognitive intervention; evidence-based nursing