Abstract: Objective: To investigate the characteristics of mastery in young and middle-aged patients with peritoneal dialysis and to explore its influencing factors. Methods: Following convenient sampling, a total of 238 young and middle-aged patients with peritoneal dialysis were investigated by using the general information questionnaire, Personal Mastery Scale (PMS), Herth Hope Index (HHI) and the Revised Piper Fatigue Scale-Chinese Version (RPFS-CV). Multiple linear regression was used to explore the main influencing factors of mastery among these patients. Results: The mean score of the PMS was 26.02±3.81. Multiple linear regression analysis showed that patients' educational background, monthly income per family member, the level of serum creatinine, hope, and degree of fatigue were the influencing factors for mastery among these patients (P<0.05). Conclusion: The level of mastery in young and middle-aged patients with peritoneal dialysis is moderate but still needs to be improved, more attention should be paid to those patients with low educational level, low income with high serum creatinine level; health providers should provide guidance to patients and assist them to establish life hope during clinical practice, and encourage them to participate in moderatephysical activities, decrease the degree of fatigue by adapting physical, mental and traditional Chinese medicine therapies, therefore to promote their mastery level.

Key words: young and middle-aged patients; peritoneal dialysis; mastery; influencing factors; hope; fatigue