Abstract: Objective: To determine the risk factors of acquired dysphagia in ICU patients by Meta-analysis. Methods: Studies were identified through a search of the Cochrane Library, PubMed, Embase, Web of Science, CNKI, Wanfang Data, VIP Database and SinoMed from inception to November 2020. Data sets from published cohort studies, case-control studies and studies with other research design with data on risk factors for acquired dysphagia in ICU patients were screened for eligibility, and RevMan 5.3 software was used for Meta-analysis. Results: A total of 14 articles were included. The total sample size was 3395, and 11 risk factors were included. The combined effects of mechanical ventilation time, tracheotomy and age were statistically significant (P<0.05), the OR (95% CI) were 1.97 (1.64-2.36), 1.63 (1.21-2.21) and 1.05 (1.03-1.07), respectively. Conclusion: The risk factors for acquired dysphagia in ICU patients reported in this study included mechanical ventilation, tracheotomy and age.

Key words: ICU, dysphagia, risk factors, systematic review