Abstract: Objective: To analyze the available evidences on aspiration prevention during enteral nutrition in critically ill patients with abdominal hypertension. Methods: We searched the data from Best practice (BMJ), Up To Date, Guidelines International Network (GIN), National Guideline Clearinghouse (NGC), Cochrane Library, PubMed, Web of Science, CNKI, WanFang Database, VIP to collect literatures including guidelines, evidence summary, best practice recommendations reports, expert consensus report, systematic reviews and original guideline. Results: Totally 17 articles were selected, including 8 systematic reviews, 3 guidelines, 2 evidence summaries, 4 best practice recommendations reports. Finally 20 items of evidences were summarized with regard to identifying risk factors of abdominal hypertension and aspiration, enteral nutrition management, abdominal hypertension management, airway management, drug management and clinical monitoring. Conclusion: It is expected to provide useful information for nurses to prevent aspiration of patients in clinical practice, and improve patients safety and satisfaction.

Key words: critically ill patient; abdominal hypertension; enteral nutrition; aspiration; evidence-based nursing