关键词: 肿瘤；导管相关性感染；危险因素；Meta分析

Abstract: Objective: To investigate the risk factors for catheter-related infection in cancer patients. Methods: Articles on risk factors for catheter-related infection in cancer patients were retrieved from PubMed, Cochrane Library, Web of Science, EBSCO, CBM, CNKI and Wanfang databases. A Meta-analysis was performed after the combination of outcome indicators. Sensitivity analysis and publication bias was checked. Results: In the 19 articles, a total of 11,672 patients were included, 957 patients were infected, with an incidence rate of 8.2%. Twenty-six risk factors were involved. Excluding the risk factors mentioned in only one article, the remaining 14 risk factors were analyzed. Age (>60 years), comorbidities, hematological tumor, puncture times (>2 times), indwelling time (>7 months), right arm, catheter adjustment, chemotherapy (>6 times), low immune function, TPN infusion, summer catheterization associated with central venous catheter-related infections were statistically significant (P<0.05). Conclusion: Catheter-related infection in cancer patients is affected by multiple factors, and it is important to regulate nursing techniques to reduce the risk and prevent catheter-related infection.

Key words: cancer; catheter-related infection; risk factor; Meta-analysis