Abstract: Objective: To review the application of evidence for prevention of Oral Mucosal Pressure Injury (OMPI) in patients with orotracheal intubation, analyze the obstacles and promoting factors, to provide reference for clinical practice. Methods: Based on the JBI evidence-based health care model as the theoretical framework, the evidence introduced into clinical practice was determined, the review indicators were constructed, the obstacles and promoting factors of evidence application were analyzed, and the change strategies were formulated. Results: A total of 21 review indicators were developed. However, the implementation rate of 11 indicators was less than 60%, and the implementation rate of 4 indicators was 0. The main obstacles in evidence-based practice included the lack of assessment tools for OMPI risk insufficient prevention procedures, nurses' shortage of relevant knowledge, and inadequate equipment in the department, etc. As to the promotion factors, there were the strong management support and nurses' active participation in the process, according to which the corresponding strategies for change were formulated. Conclusion: The review indicators developed in this study based on the evidence are scientific, comprehensive, and operable. Yet there is still a big gap between the evidence and clinical practice for the prevention of OMPI in patients with orotracheal intubation. Clinical strategies for change can be implemented according to the obstacles and promoting factors to enhance the transformation of the evidence into clinical practice.

Key words: intensive care unit; tracheal intubation; oral mucosal; pressure ulcer; evidence review; evidence-based practice