Abstract: Objective: To evaluate the reliability and validity of the Chinese version of the Pediatric Quality of Life Inventory Infant Scales (PedsQLTM Infant Scales), and to provide a tool for the assessment of infant quality of life in China. Methods: A total of 578 infants aged 1-12 months who received outpatient pediatric healthcare services from December 2023 to January 2024 in 29 community health service centers in Shanghai were selected by multi-stage probability sampling method. The caregivers of infants were surveyed using the Chinese version of the PedsQLTM Infant Scales. Results: The correlation coefficients between the scores of each item and the total score of the Chinese version of the PedsQLTM Infant Scales ranged from 0.544 to 0.799 (P<0.05). There were statistically significant differences in the critical values of each item between high and low groups (P<0.05). The overall Cronbach’s α coefficient for the scale was 0.967, and the split-half reliability coefficient was 0.888. The cumulative variance of exploratory factor analysis was 71.017%. Confirmatory factor analysis result demonstrated a good fit for the model. Conclusion: The Chinese version of the PedsQLTM Infant Scales for infants aged 1-12 months exhibits good reliability and validity, and it provides a scientifically reliable tool for the evaluation of infant quality of life in China.

Key words: Health-Related Quality of Life; infant; reliability; validity