Abstract: Objective: To investigate the medication safety ability of nurses in secondary and above medical institutions in China, and analyze its influencing factors, so as to provide reference for improving nurses' medication safety ability. Methods: From April to May 2023, convenience sampling was used to conduct a cross-sectional survey of 5193 nurses in secondary and above medical institutions using the general information questionnaire and Medication Safety Competence Scale. Multiple linear regression was used to analyze the influencing factors of nurses' medication safety ability. Results: The total score of medication safety ability of nurses in secondary and above medical institutions was 161.21±20.78, and the item average score was 4.48±0.58. Among the six dimensions, the dimension of influencing factor management had the highest average score, and the dimension of improving medication safety had the lowest score. Multiple linear regression analysis showed that nursing experience, education background, hospital level, professional title, the number of patients cared for per day, and the department were the influencing factors of nurses' medication safety ability (P<0.05). Conclusion: The medication safety ability of nurses in secondary and above medical institutions is good. It is necessary to take appropriate medication safety ability training programs in combination with the personal characteristics of nurses, the level of hospital, the type of department and the medication environment, and pay attention to the improvement of medication safety issues to further improve the medication safety ability of nurses in China.

Key words: medication safely ability; nurse; influencing factor; nursing risk