Abstract: Objective: To introduce the Medication Adherence Self-efficacy Scale-Revision (MASES-R) to China, and to test its reliability and validity. Methods: Authorization was obtained from the original authors of MASES-R. Cross-cultural revision of the MASES-R was conducted according to the guidelines recommended by the American Academy of Orthopaedic Surgeons Evidence-based Medicine Committee. January to March 2019, Totally 445 patients with hypertension were recruited in Changsha through convenience sampling from a tertiary hospital and investigated by using the Chinese version of MASES-R(MASES-R-C).Reliability and validity of the scale were assessed. Results: In MASES-R-C, the correlation coefficient between each item and the total score ranged from 0.660 to 0.919, and the correlation coefficient between each item ranged from 0.514 to 0.872. The I-CVI of each item ranged from 0.83 to 1.00, and the S-CVI was 0.961. KMO value of exploratory factor analysis was 0.920, Bartlett's spherical test chi-square value was 6405.74 (P<0.001), values of factor loading ranged from 0.640 to 0.916, and the total variance interpretation rate was 68.72%. In confirmatory factor analysis, average variance extracted (AVE) value was 0.647, composite reliability (CR) value was 0.947, and the standardized loading coefficient for each item ranged from 0.597 to 0.932. The single-dimensional model fit well. The Cronbach's α coefficient of the scale was 0.960, Spearman-Brown split-half reliability was 0.927, and the test-retest reliability was 0.868. Conclusion: The psychometric properties of Chinese version of MASES-R proved to be good. MASES-R-C can be used as a tool to evaluate the medication adherence self-efficacy of patients with hypertension in China.

Key words: hypertension; medication adherence; self-efficacy; cross-cultural adaptation; reliability; validity