Abstract: Objective: To explore the application effects of Hospital-to-Home (H2H) nutrition management based on the Nutrition Care Process Model (NCPM) in patients with pancreatic cancer, and to provide reference for the continuous nutrition management during hospitalization and at home for pancreatic cancer patients. Methods: A total of 143 pancreatic cancer patients in a tertiary grade A hospital in Wuhan were recruited through convenience sampling from March to September 2024 and randomly divided into an intervention group of 71 cases and a control group of 72 cases. The control group received conventional nutrition management, while the intervention group received H2H nutrition management based on the NCPM model. The nutritional indicators, compliance rate of Oral Nutritional Supplementation (ONS), hospitalization time, and quality of life were compared between the two groups. Results: After 3 months of discharge, the NRS 2002 score and PG-SGA score of the intervention group were (2.77±0.68) points and (3.75±0.92) points respectively, both lower than those of the control group (3.12±0.74) points and (4.59±1.14) points (P<0.05); the serum albumin, prealbumin, transferrin levels, and BMI of the intervention group were all higher than those of the control group (P<0.05); the ONS compliance rate of the intervention group was higher than that of the control group (92.96% vs 80.56%, P<0.05); the hospitalization time of the intervention group was shorter than that of the control group (P<0.05); the EORTC QLQ-C30 score of the intervention group was higher than that of the control group (P<0.05). Conclusion: The H2H nutrition management based on the NCPM model can improve the nutritional status and the quality of life of pancreatic cancer patients.

Key words: pancreatic cancer; Nutrition Care Process Model; Hospital-to-Home nutrition management; quality of life