Abstract: Objective: To construct an evidence-based Central Venous Access Devices (CVAD) safety management information platform (hereinafter referred to as the platform) and evaluate its application effects to enhance the compliance of nurses in evidence-based practice, promote the clinical transformation of evidence, reduce catheter-related complications and improve catheter safety. Methods: Literatures on the placement, maintenance and removal of CVADs for children were searched to extract specific measures which were then assessed and adopted according to feasibility, appropriateness, meaningfulness and effectiveness (FAME). Later the way of embedding in the information system was formulated to form an evidence transformation information platform, which was officially and thoroughly applied in January 2020. Indicators such as CVAD-related complications and unplanned extubation in hospitalized children were compared before (2019) and after (2020-2023) the application of the platform. Results: After the implementation of the platform, the rate of CVAD-related complications and unplanned extubation in hospitalized children decreased significantly (P<0.001). Conclusion: The construction and application of the platform can ensure the information management of the whole process from catheter placement, maintenance to extubation, improve nurses’ compliance to evidences in practice to boost the homogenization of patient health education and reduce catheter-related complications. Meanwhile, the platform can provide timely and objective data and early warning, so that information communication among all departments in a hospital can be realized to improve catheter safety management for patients.

Key words: Central Venous Access Devices; child catheter safety; information platform; evidence-based practice; smart hospital