Abstract: Objective: To design a checklist for safe infusion of enteral nutrition tubes and apply it to clinical practice, in order to improve the safety and efficiency of enteral nutrition infusion. Methods: Based on literature review, group discussion and expert consultation, a checklist for safe enteral nutrition infusion was designed, and the nutritional status, incidence of adverse events including tube blockage, tube slippage, aspiration, abnormal blood glucose and incidence of enteral nutrition intolerance were compared before and after the checklist was applied in practice. Results: After the application of the checklist, the incidence of adverse events, including tube blockage, pipeline slippage, abnormal blood glucose, and the incidence of enteral nutritional intolerance were significantly lower than those of control group (P<0.05). The nutritional status of the patients at discharge was better than that of control group (P<0.05). Conclusion: The application of the checklist for the safe of enteral nutrition infusion can standardize the enteral nutrition infusion process, improve nurses' compliance and decision-making ability, improve the nutritional status of patients, effectively reduce the incidence of enteral malnutrition and the rate of enteral nutrition intolerance, thereby improving the safety of enteral nutrition infusion.

Key words: enteral nutrition; feeding tube; safety; pipe blockage; feeding intolerance; checklist