Abstract: Objective: To analyze the research status and issues related to patient safety in China from 2006 to 2016. Methods: All literatures related to patient safety were sourced in the Wan- fang Database, VIP Database and China National Knowledge Infrastructure (CNKI) from 2006 to 2016. The literatures were analyzed using bibliometric analysis method. Results: A total of 218 articles related patient safety published in 106 journals were sourced. There is a trend of growth in the number of the articles since 2010, but a downward trend in recent two years. The authors came from 180 facilities, most of which were medical universities and affiliated hospitals (61.47%). Guangdong, Shanghai and Sichuan enjoyed the most share of articles. Clinical experience reports accounted of 51.83%, questionnaire survey studies accounted of 14.22%, only 8.71% were experimental studies. Tertiary and secondary hospitals were the major research facilities. Patients (including family members) and health care workers were the main subjects of the studies. The research topics mainly focused on the patients and health care workers's attitudes towards patients safety, the related factors, the participating methods and the effectiveness evaluation. Totally 8.26% of the research papers were funded by the government. Conclusion: The importance of patientsafety has attracted attention from the researchers in recent years, but the studies still have some limitations. The multi-center, randomized controlled studies aresuggested too provide evidence-based information and to enhance the quality of nursing management in patient safety.