Abstract: Objective: To investigate the current patient safety nursing status from clinical nurses' self-reports and analyze the influence factors. Methods: Totally 1 646 nurses from four hospitals were investigated by Chinese version of the Patient Safety Nursing self-rating scale. Results: The patient safety nursing status was in the upper level with the mean score of (188.37±14.12) and 94.19% score rate. Nurses with different age, department, education level, and professional title reported different patient safety nursing score (P<0.05). Multiple linear regression analysis showed that the influence factors included work years in nursing, departments and professional title. Conclusion: The nursing administrators could carry out relevant training activities about patient safety on the basis of work years, professional titles and departments of clinical nurses respectively, to improve the ability of clinical nurses' self-management and safety awareness for ensuring the patients' safety.