Abstract: Objective: To explore the application effect of the integrated management model of ward-outpatient-family among patients with Mild Cognitive Impairment (MCI). Methods: Ward-outpatient-family integrated management model was used among 70 patients with MCI, and the patients were evaluated by MMSE, MoCA, and ADL before and after the intervention. Results: The mean scores of MMSE and MoCA of the patients after intervention were higher than those before intervention (P<0.05), and the ADL scores had no significant difference before and after intervention (P>0.05). Conclusions: Ward-outpatient-family integrated management model construction plays an important role in improving the cognitive function of patients with MCI.