Abstract: Objective: To summarize the evidence of inhaled therapy with inhalation devices in patients with COPD, and to provide references for clinical practice. Methods: The literature related to the evidence of inhaled medication management in COPD patients was systematically searched from domestic and foreign databases and websites until June 13, 2023. Researchers evaluated literature quality and extracted evidence according to the literature evaluation criteria. Results: A total of 21 literatures were included, including 5 clinical decisions, 4 guidelines, 2 evidence summaries, 5 systematic reviews, 1 randomized controlled trial and 4 expert consensus. Twenty-seven pieces of evidence were summarized from eight aspects: multidisciplinary cooperation, combination medication regimen, selection of inhalation device, evaluation of inhalation device usage technique, evaluation of inhaled medication compliance, health education for inhaled medication, follow-up and management, and effects evaluation. Conclusion: This study summarized the current evidence on inhaled medication management in COPD patients and provided scientific and effective evidence-based reference for healthcare providers to manage inhaled medication, so as to improve the correctness of inhaled medication in COPD patients.

Key words: COPD; inhalation devices; medication management; evidence summary