Abstract: Objective: To construct an intervention program based on the concept of Child Life for the symptom group of children with Acute Leukemia. Methods: Under the guidance of the concept of Child Life, through literature review, a preliminary intervention plan for the symptom group of children with Acute Leukemia was formulated, the specific content, mode and time of the intervention were determined through Delphi expert consultation. Results: The effective recovery rates of the two rounds of expert consultation questionnaires were 79.0% and 100.0% respectively, the expert authority coefficient was 0.823, and the expert coordination coefficient of the two rounds was 0.413 and 0.135, respectively. Finally, a symptom group intervention program with an intervention period of 2 months was formed, including 3 first-level items, 8 second-level items and 18 third-level items in the developmental game stage, medical simulation game stage and supportive game stage. Conclusion: The intervention program based on the concept of Child Life for the symptom group of children with Acute Leukemia has reliable results and has certain feasibility.

Key words: Child Life; Acute Leukemia; child; symptom group; intervention program; Delphi method