Abstract: Objective: To investigate the knowledge, attitude and practice of the ICU nurse specialists to the early mobilization of patients with mechanical ventilation and to explore the influential factors. Methods: A self-designed general information questionnaire, and the knowledge, attitude and practice questionnaire about early mobilization of patients with mechanical ventilation were used to collect data, and the ICU nurses who participated in the ICU nurse specialists training project in the First Affiliated Hospital of Chongqing Medical University from 2016 to 2018 were included in the study. Results: The score of early mobilization knowledge of mechanical ventilation patients was 7.44±1.51, the score of attitude was 25.42±2.89, and the score of behavior was 24.79±6.64. Multiple linear regression analysis showed that the training was the influential factor of ICU nurse specialists' knowledge, attitude and practice (P<0.01). Conclusion: ICU nurse specialists have good knowledge and attitude towards early mobilization of patients with mechanical ventilation, but management behaviors is inconsistent with attitude. Managers should pay more attention to the nurse training on early mobilization of patients with mechanical ventilation.

Key words: ICU nurse specialist; mechanical ventilation; early mobilization; investigation