Abstract: Delirium is a common cognitive dysfunction syndrome in ICU patients with high incidence, and it also can lead to a series of short-term and long-term adverse outcomes. This paper reviews the ABCDEF bundles from the perspective of intervention methods, clinical effects and unique role of nurses in the prevention and treatment of ICU delirium, and to provide reference for the prevention and management of ICU delirium.

Key words: Intensive Care Unit; ICU delirium; ABCDEF bundle; prevention; management; review