Abstract: Objective: To set up the management information platform of Venous Thromboembolism (VTE), and establish the assessment-alert-intervention procedure of VTE. Methods: Firstly, the authors designed the framework of VTE management information system. Secondly, they established the preliminary draft of the platform, and then conducted the pilot run in several selected units, collected the feedback to improve the platform. Finally, they generalized the use of the platform widely. Results: They set up a preferable framework of VTE management information platform. The platform increased the rates of assessment and the physical prevention measures and implementation (P<0.05). Conclusion: The VTE management information platform could improve the management efficiency.