Abstract: Objective: To examine the knowledge, attitude and practice regarding Chemotherapy-induced Peripheral Neuropathy (CIPN) assessment and management among oncology nurses, and identify the barriers of CIPN assessment and management as well as nurses' needs of continuing education. Methods: The self-designed questionnaire was used to collect data. Univariate and multivariate analysis were used to identify the influencing factors of oncology nurses' knowledge, attitude and practice regarding CIPN assessment and management. Results: The average scores of knowledge, attitude and practice regarding CIPN assessment and management were 9.16±1.93, 27.96±6.65 and 25.84±12.48 respectively, accounting for 57.3%, 77.7% and 53.8% of the full score. Nurses' practice were influenced by their training experience and professional title. Barriers of performing CIPN assessment were do not know how to perform neurologic assessment (68.9%), no proper assessments (57.9%), and do not know how to evaluate (55.7%). Nurses preferred to take part in group study (76.4%) and academic workshop (71.2%) to improve knowledge. Conclusion: Nurses' knowledge, attitude and practice regarding CIPN assessment and management needed to be improved. Managers should organize specific training programs to improve nurses' ability, and also develop proper assessment tool for CIPN.