关键词: 胶质瘤；肠内营养；腹内压；影响因素

Abstract: Objective: To analyze the influencing factors of Intra-Abdominal Pressure (IAP) in patients with glioma after operation, and to provide reference for effective Enteral Nutrition support in patients with glioma surgery. Methods: From October 2017 to April 2018, 164 patients with postoperative enteral nutrition for glioma treatment in a neurological intensive care unit in a tertiary grade A hospital in Beijing were investigated. The IAP was measured before and after enteral nutrition to analyze the factors affecting IAP. Results: There was a statistically difference in IAP between patients with glioma before and after enteral nutrition. The Body Mass Index (BMI), Positive End-Expiratory Pressure (PEEP), APACHE II and IAP were positively correlated (r=0.631, 0.455, 0.342, P<0.05), and the Glasgow Coma Scale (GCS) score and IAP were negatively correlated (r=-0.231, P<0.001). BMI, PEEP, APACHE II and GCS score were the influencing factors of IAP, which could explain 41.4% variation. Conclusion: In the process of Enteral Nutrition, patients with glioma after operation should be paid attention to the changes of IAP. This study provides a basis for clinical nursing monitoring indicators, in order to ensure the safety of patients' nutritional support.

Key words: glioma; Enteral Nutrition; Intra-Abdominal Pressure; influencing factors