Abstract: Objective: To evaluate the effect of Fast-Track Surgery (FTS) during perioperation period for urology surgery patients. Methods: We selected 100 urology surgery patients who accept operation treatment as the research object, and through randomized single blind digital way, they were divided into the control group and the observation group with 50 cases in each group. The control group were given conventional operation nursing, the observation group throughout the FTS concept in the perioperative period nursing process. We compared two groups of patients with perioperative heart rate, blood pressure and temperature stress changes, and recorded two groups patients of postoperative hospitalization time, solid food tolerance time,ambulation time, two groups of patients' satisfaction survey. Results: ① The observation group patients before 30 minutes of heart rate, blood pressure values were better than the control group,it had significant difference (P<0.01), but no statistical difference of temperature value (P>0.05); postoperative 30min, observation group of patients with heart rate, blood pressure and temperature values were relatively stable than control group, and had statistically significant difference (P<0.01). ② The observation group patients' solid food tolerance time, ambulation time and postoperative hospitalization time were shorter than the control group(P<0.01). ③ The observation group patients' satisfaction rate significantly more than the control group, the difference had statistically significant (P<0.01). Conclusion: The concept of FTS can meet the demand of department of urology patients during perioperative period, shorten the recovery time, improve the patients' satisfaction to nursing work.