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主办:国家卫生健康委医院管理研究所
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• 特别策划·静脉治疗管理 • 上一篇    下一篇

肿瘤患者PICC导管相关静脉血栓形成影响因素Meta分析

于瑞 陈利芬   

  1. 中山大学附属第一医院护理部
  • 出版日期:2016-06-25 发布日期:2016-06-25

Risk factors of venous thromboembolism associated with peripherally inserted central catheters among cancer patients: a Meta-analysis

  • Online:2016-06-25 Published:2016-06-25

摘要: 目的:综合分析肿瘤患者PICC 导管相关静脉血栓形成的危险因素,为预防PICC 导管相关静脉血栓形成提供理论依据。方法:计算机检索Web ofScience、PubMed、Cochrane Library、OVID EBM Reviews、 CNKI、万方数据、CBM 及VIP,并辅以手工检索、文献追溯等方法收集符合标准的文献,采用Stata 12.1 软件进行合并分析。结果:纳入符合标准的文献6 篇,合计样本量1277 例,其中血栓组253 例,对照组1024 例,血栓发生率为19.81%。Meta 分析结果显示,化疗史、糖尿病、高血压、COPD、活动量减少与PICC 导管相关静脉血栓形成有关。结论:化疗史、糖尿病、高血压、COPD、活动量减少是PICC 导管相关静脉血栓形成的危险因素。

Abstract: Objective: To analyze the risk factors of venous thromboembolism associated with peripherally inserted central catheters (PICC) among cancer patients, and to provide theoretical basis for prevention venous thromboembolism associated with PICC among cancer patients. Methods: We searched the related papers from the Web of Science, PubMed,Cochrane Library, OVID EBM Reviews, CNKI, Wan Fang Databases, CBM and VIP. The Stata 12.1 software was used to conduct the meta-analysis. Results: Six studies were included in the study. The sample size was 1277 with 253 cases in venous thromboembolism group and 1024 cases in control group. The incidence rate of venous thromboembolism associated with PICC was 19.81%. Meta-analysis showed that the risk factors were history of chemotherapy, diabetes, hypertension, COPD,and less activity. Conclusion: The risk factors of venous thromboembolism associated with PICC among cancer patients are history of chemotherapy, diabetes, hypertension, COPD, and less activity.