Abstract: Objective: To evaluate the hierarchical transport mode to improve the safety and feasibility of the intrahospital transportation in critically ill patients, and to ensure the safety of critically ill patients. Methods: In the study,patients in the control group were treated with routine transportation method. In experimental group, the hierarchical mode of transportation was implemented, which includes the assessment on the patient's condition before transportation,classification of the patient's condition, transport personnel, transport equipment and medicines according to the condition of their grades. Results: The transit time of experimental group is shorter than the control group in the transit to the CT.And the difference in intensive care unit, the intervention room and the operation room time were statistically significant(P<0.05). However, the transmit time to the general ward did not show significant difference between the two groups(P>0.05). Compared to the control group, the incidence rate of adverse events in the experimental group has significantly decreased. The incidence rate of adverse events related to the disease was 2.8% ( 2=6.19, P<0.05), to the transferring persons was 7.2% ( 2=4.94, P<0.05), and to the equipment was 3.9% ( 2=5.27, P<0.05). Conclusion: The hierarchical transport mode can reduce the incidence rate of adverse events. The safety of transport could be ensured and the transit time could be shorted by the hierarchical transport mode.