肿瘤患者PICC导管相关血栓形成危险因素的研究

肿瘤患者PICC导管相关血栓形成危险因素的研究

于瑞陈利芬周雪梅何佩仪侯秋秀郑锦萍

中山大学附属第一医院器官移植一区（于瑞）；护理部（陈利芬，周雪梅）；血液一区（侯秋秀）；妇科二区（郑锦萍）；广州市第一人民医院肿瘤科（何佩仪）

出版日期:2016-10-25 发布日期:2016-10-25

The risk factors of thrombosis associated with Peripherally Inserted Central Catheters among cancer patients

Online:2016-10-25 Published:2016-10-25

摘要/Abstract

摘要： 目的：分析肿瘤患者 PICC 导管相关血栓形成的危险因素。方法：收集广州市两所三级甲等综合医院 2014 年 1月1日至 12 月31日留置 PICC 肿瘤患者一般人口学资料、置管前一周内血样检查结果、病史资料、置管资料及置管 3 个月内并发症发生情况，采用 Logistic 回归分析筛选 PICC 导管相关血栓形成危险因素。结果：确诊癌症 7 个月及以上、肿瘤转移、有置管期间放疗史、置管目的为输注脂肪乳 / 甘露醇等是肿瘤患者 PICC 导管相关血栓形成的危险因素， OR 值及其 95% CI 分别为 1.832 （1.092～3.386）、2.358 （1.113 ～ 4.996）、4.348（1.902～ 9.941）、3.442 （1.044 ～11.341）。结论：肿瘤患者 PICC 导管相关血栓形成的危险因素包括确诊癌症7 个月及以上、肿瘤转移、有置管期间放疗史、置管目的为输注脂肪乳 / 甘露醇等。

Abstract: Objective: To determine the risk factors of thrombosis associated with Peripherally Inserted Central Catheters among cancer patients. Methods: The research was conducted in two tertiary Grade A general hospitals in Guangzhou. It was a retrospective study from January to December, 2014. We recruited the eligible patients and investigated their demographic data, medical history and complications within 3 months of catherization, and then used multiple logistic regression analysis to determine PICC related thrombosis risk factors among cancer patients. Results:Risk factors positively associated with thrombosis were diagnosed cancer for more than seven month, metastases, history of radiation, and fat emulsion/mannitol infusion, and the value of OR and 95% CI were 1.832 (1.092-3.386), 2.358 (1.113-4.996), 4.348 (1.902-9.941), 3.442 (1.044-11.341) respectively. Conclusion: The risk factors of PICC related thrombosis among cancer patients included diagnosed cancer for more than seven month, metastases,history of radiation, fat emulsion/mannitol infusion.

于瑞陈利芬周雪梅何佩仪侯秋秀郑锦萍. 肿瘤患者PICC导管相关血栓形成危险因素的研究[J]. , 2016, 16(10): 1326-1330.