Abstract: Objective: To construct an objective and comprehensive evaluation index system for registered nurses. Methods:Delphi methods were used to develop the evaluation index system of clinical practice competencies for registered nurses. Two rounds of professional consultations were conducted among 45 experts allover China. Results: The final evaluation indexes of clinical practice competencies were comprised of 4 first-level indexes,16 second-level indexes and 60 criterions. The firstlevel indexes included nursing practice motivation, general ability of nursing practice, special ability of nursing practice and situation ability of nursing practice. Conclusions: This study process is rigorous with highly level of enthusiasm, authority and team coordination amongexperts,and the results could be used as guidance for both clinical practice and continuing education of registered nurses.