Abstract: Objective: To investigate the level of symptom intrusiveness in patients with Malignant Fungating Wounds and analyze the influencing factors. Methods: From January 2019 to May 2021, 132 patients with Malignant Fungating Wounds were selected as the research subjects by convenience sampling method in a tertiary grade A hospital in Nanning. The general information questionnaire and the Symptom Intrusiveness Rating Scale and other tools were used to evaluate the level of symptom intrusiveness of patients with Malignant Fungating Wounds. Using multiple linear regression to analyze the influencing factors. Results: The total score of symptom intrusiveness in patients with Malignant Fungating Wounds was (55.42±14.21). The scores of the dimensions were functional status (19.50±4.73), social relationship (17.50±6.12), mental health (18.42±4.55). Multiple linear regression results showed that gender, wound exudation amount, wound odor, wound itching, dressing change frequency and psychological distress were the influencing factors of symptom intrusiveness of patients with Malignant Fungating Wounds (P<0.05), accounted for 79.7% of the total variation. Conclusion: Patients with Malignant Fungating Wounds have higher symptom intrusiveness level. Nurses should pay attention to the patient's wound or tumor-related symptoms, to help patients manage their symptoms, guide patients to actively deal with existing symptoms and illnesses, give psychological support and counseling, improve patients' quality of life.

Key words: Malignant Fungating Wounds; symptom intrusiveness rating; psychological distress; influencing factors