Abstract: Objective: To evaluate the quality and analyze the contents of the clinical practice guidelines on childhood asthma, and to provide references for the construction of health education program for children with asthma in China. Methods: Guidelines on childhood asthma from websites of clinical practice guidelines, asthma professional organizations and databases published internationally in recent 5 years were searched, then the quality evaluation of included guidelines was carried out using AGREE II. Results: We identified 9 guidelines, of which 8 were in English, one was in Chinese, and 6 were evidence-based guidelines. The average AGREE II standardized scores in 6 domains were 52.78% (scope and purpose), 37.04% (stakeholder involvement), 27.89% (rigor of development), 47.84% (clarity of presentations), 31.25% (applicability) and 24.54% (independence), respectively. For overall quality, 5 of them were grade B and 4 of them were grade C. Totally 35 recommendations of education and management on childhood asthma were extracted. Conclusion: The qualities of included guidelines were at the average level. The rigor of development, clarity of presentations, applicability and independence of guidelines need to be improved. We should learn from foreign high-quality evidence for localization practice, and to guide the development of asthma education and management of children in China.

Key words: children; asthma; clinical practice guidelines; quality evaluation; AGREE II