Abstract: Objective: To investigate the relationship among career resilience, career plateau of emergency and critical care nurses. Methods: A total of 352 emergency and critical care nurses from five general tertiary grade A hospitals in Nanjing were recruited using convenience sampling method and investigated by questionnaires. Results: The total score of career resilience was (3.32±0.52), and the total score of career plateau was (3.24±0.75). Career resilience was significantly negatively correlated with career plateau (P<0.01). After controlling demographic variables, career resilience could explain 27.2% for the variances of career plateau. Conclusion: Emergency and critical care nurses were on latent plateau. Career resilience was in the middle level. Career resilience can predict career plateau. Nurse managers can improve emergency and critical care nurses'career resilience to alleviate career plateau, and retain nurses.