Abstract: Objective: To analyze the application effects of a multidisciplinary collaborative intervention program on readiness level of adolescents with epilepsy for the transitional to adulthood, aiming to provide references for promoting clinical practice. Methods: A quasi-experimental study was conducted using convenience sampling to select 76 adolescents with epilepsy treated at a tertiary grade A hospital in Baise from June to December 2023. They were divided into two groups according to the admission ward, with 38 cases in each group. The control group received routine treatment and care, while the intervention group received a multidisciplinary collaborative intervention in addition to routine care. The scores of transition readiness, medication adherence, quality of life, frequency and duration of epileptic seizures within 3 months between the two groups were compared. Results: Scores of the Epilepsy Transition Readiness Assessment Questionnaire, Epilepsy Medication Adherence Scale, and Adolescent Epilepsy Quality of Life Questionnaire were significantly higher in the intervention group compared to the control group (all P<0.05). The intervention group had fewer seizure occurrences than the control group (P<0.05), but there were no statistically significant differences between the two groups in seizure duration and electroencephalography improvement (P>0.05). Conclusion: The multidisciplinary collaborative intervention program can effectively enhance epilepsy transition readiness, medication adherence, quality of life, and reduces seizure frequency in adolescents, providing valuable insights for supporting transitional care in clinical settings for adolescents with epilepsy.

Key words: epilepsy; adolescent; Multidisciplinary Team; transition readiness; nursing care