Abstract: Objective: To investigate the current status of doctor-nurse cooperation and to analyze the influence of doctor-nurse cooperation on nurses' working involvement. Methods: Totally 309 nurses in a tertiary Grade A hospital were recruited using convenience sampling method from February to May in 2015 and investigated by a self-designed demographic questionnaire, Nurse-Physician Collaboration Scale (NPCS), and Utreeht Work Engagement Scale (UEWS).Results: The total score of NPCS was 91.20±15.89 with the mean score of 3.65±0.64. The total score of UEWS was 51.82±9.37 with the mean score of 3.46±0.62. Relationships between doctors and nurses, doctors and nurses participating in the decision-making process of medical treatment or care, patients' information exchange were the main influencing factors of nurses working involvement. Conclusion: Improving cooperation between doctors and nurses could enhance the level of nurse working involvement and provide better quality of care for patients.