Abstract: Objective: To explore the effects of "sugar-baby follow-up" APP on children with type 1 Diabetes Mellitus(T1DM). Methods: Totally 201 children with T1DM were recruited and divided into intervention group and control group according to the follow-up time. The control group received the original transitional nursing care, while the intervention group added "sugar-baby follow-up" APP besides transitional nursing care applied in control group. The study compared the fasting blood sugar level and the lowest blood sugar level before the intervention and 3 months after the follow up. Result: There were no statistical differences (P>0.05) in fasting blood sugar and the lowest blood sugar levels between control and intervention groups before the intervened follow up; both groups have fasting blood sugar above normal range. After providing the transitional care and follow up, the fasting blood sugar level in both control and intervention groups was improved from baseline before the intervention (P<0.05); in addition, the intervention group which utilized "sugar-baby follow-up" App had a lower fasting blood sugar than the control group (P<0.01); there was no statistical difference in the lowest blood sugar level achieved in the control group before and after the follow up care (P>0.05); however, the intervention group with App usage was able to avoid hypoglycemia and the blood sugar level was in safe rage after the intervention (P<0.01) and the lowest blood sugar level was also higher than the control group, the difference was statistically significant (P<0.01). Conclusion: The "sugar-baby follow-up" APP could help children with T1DM manage their blood glucose better.