Abstract: Objective: To develop and implement courses for distance nursing education based on clinical practice research findings. Methods: The course "Comprehensive Training for Nursing Clients with Specialized Conditions" for undergraduate students in Peking University School of Distance Learning was developed based on clinical practice research findings. The effect of education was evaluated. Results: All of the students passed the course, the average score was 85.31±7.61. 60.0% of the students thought the course was difficult, 53.3% of the students thought the course could meet most of their learning needs. Conclusion: The distance nursing education courses based on clinical practice research findings can improve students' comprehensive ability of nursing practice.