Abstract: Objective: To translate the French version of ICU patients' discomfort into Chinese, and to test the reliability and validity of the Chinese version of IPREA. Methods: The IPREA was translated and adapted according to Chinese culture. The reliability and validity of Chinese version of IPREA was tested with 185 ICU patients. Results: The Chinese version of IPREA consisted of 17 items in three dimensions. The correlation coefficient between each dimension and the total score was 0.562~0.899,and the content validity index was 0.920. The Cronbach's α coefficient for the overall scale was 0.834, and 0.705~0.782 for the three dimensions. The test-retest reliability was 0.871 for the overall scale.Three factors were extracted by factor analysis, which could explain 60.066% of the total variance. Conclusion: The Chinese version of IPREA has acceptable reliability and validity. It can be used to measure the discomfort level of ICU patients in Chinese medical environment.