Abstract: Objective: To examine the relationship between stigma and the quality of Life among convalescent schizophrenia patients, and to explore the mediating effect of social support and coping style between stigma and the quality of life. Methods:The perceived Devaluation-Discrimination Scale, Simplified Coping Style Questionnaire, Social Support Rating Scale, and the Schizophrenia Quality of Life Scale were used to investigate the convalescent schizophrenia patients. Results: Structural equation model fit index: χ2/df=1.673, GFI=0.950, AGFI=0.903, RMSEA=0.061. Stigma, social support and coping style among convalescent schizophrenia patients could predict the quality of life directly. Social support and coping style played a mediating role between stigma and the quality of life. Conclusions: Mental professionals should pay more attention to stigma effect on quality of life among convalescent schizophrenia patients in their clinical practice.Based on summarizing the different paths, we should improve the quality of life of the patients. by path- based intervention.