Abstract: Objective: To explore the impact of case management nursing model on the quality of life,insight and treatment attitudes of schizophrenics. Methods: This study involved 55 schizophrenics in the beginning and 8 of which broke off in the middle. The case management nursing model was implemented on the aforesaid group and further elongated towards the living community. Schizophrenics were investigated with Schizophrenics Quality of Life Questionnaire (SQLS) and Insight and Treatment Attitude Questionnaire (ITAQ) at four different time spot, namely admission, discharge, 6 months after discharge and 12 months after discharge to examine the patients' quality of life and insight and treatment attitudes. Results: After intervention, the quality of life and insight and treatment attitudes of the patients were all improved (P<0.01) , while that of 6 months and 12 months after discharge have been decreased in different levels, especially in 12 months after discharge. Conclusion: The case management nursing model can effectively improve the quality of life, insight and treatment attitudes of the patients. The implementation of case management nursing model during hospital stay shows significant effects.