Abstract: Objective: To conduct a scoping review of the exercise rehabilitation in patients with hemophilia arthropathy, and to provide a reference for healthcare professionals to carry out rehabilitation. Methods: According to the method of the scoping review, the relevant literature in databases at home and abroad was systematically searched from the establishment of the database to December 31, 2023, and the data were independently screened and extracted by two researchers. Results: Twenty-four articles were included, and the age, bleeding conditions, treatments and degree of joint injury were the main screening criteria before exercise. The types of exercise were mostly mild, including resistance exercise, flexibility training, aerobic exercise, proprioceptive training, joint release and fascial release, and and a variety of exercises were combined.The intensity tended to be individualized, mostly in low and medium intensity, with progressive increments. The frequency and duration were mostly remained 4-12 weeks, 1 to 3 times per week, 30 to 60 min per time, and with a intermittent training way. The effect evaluation involved pain, bleeding, joint muscle function, mobility, quality of life and psychological status. Conclusion: Exercise rehabilitation has a positive effect in patients with hemophilia arthropathy. Current studies focus on relatively mild exercise in patients with early arthropathy and bleeding that is maintained stable. No consensus has been reached on a coagulation factor replacement regimen during this period.

Key words: exercise rehabilitation; hemophilic arthropathy; scoping review