Abstract: Objective: To evaluate the effect of Otago Exercise Program on the knee rehabilitation of patients after knee arthroplasty. Methods: CNKI, WanFang Data, VIP, FMRS, PubMed, Web of Science and Cochrane Library databases were searched, retrieved randomized controlled trials of rehabilitation exercise after knee arthroplasty using Otago Exercise Program. Retrieval time limit was from the establishment of the database to April 30th 2021. Two researchers independently completed the literature screening, data extraction and methodological quality evaluation of the included literature. RevMan 5.3 software was used for Meta-analysis. Results: A total of 6 randomized controlled trials were included. The Meta-analysis results showed that the knee flexion after Otago Exercise Program [SMD=10.71(7.92, 13.50), P<0.05], hospital for special surgery knee score [SMD=7.66 (5.55, 9.77), P<0.05], and Modified Falls Eglcacy Scale score [SMD=3.87 (2.02, 5.71), P<0.05] were higher than conventional rehabilitation exercises, but the difference of Berg Balance Scale score [SMD=1.96(-1.74, 5.67), P>0.05] was not statistically significant. Conclusion: Otago Exercise Program can promote the recovery of knee joint function in patients after knee arthroplasty and reduce the occurrence of falls. There were no reports of adverse events. However, the included studies were limited, need to be further verified by more high-quality studies.

Key words: Otago Exercise Program; knee arthroplasty; balance; Meta-analysis