Abstract: Objective: To explore the prognosis and risk factors of patients with proximal Deep Venous Thrombosis (DVT). Methods: Totally 72 patients with proximal DVT were investigated from January 2014 to December 2014. The incidence and risk factors of death related to Pulmonary Embolism (PE), VTE recurrence, Post-Thrombotic Syndrome (PTS) were analyzed. Results: Total 22(30.6%) patients developed poor prognosis, including 2 patients died (2.8%), 4 patients with VTE recurrence (5.6%) and 16 patients with PTS (22.2%). Logistic regression analysis indicated that risk factors were non-standardized anticoagulant therapy, high D-Dimer concentrations after 3 months oral anticoagulation treatment and inherited thrombophilia. Conclusion: The incidence of poor prognosis in patients with proximal DVT is high. Nurses should provide continuity of care to patients with DVT, ensure them with standardized anticoagulant therapy, and monitor the effects of anticoagulant therapy with D-Dimer. Nurses should provide information to patients with inherited thrombophilia to avoid acquired risk factors as well.

Key words: Deep Vein Thrombosis (DVT); prognosis; risk factors